Nipple-sparing mastectomy: Where are we now?

Abstract 

Surgical treatment of breast cancer has evolved from radical mastectomy with routine removal of the nipple–areolar complex (NAC) to breast conservative therapy with preservation of the breast and NAC. When breast conservation is not appropriate or the patient desires mastectomy for risk reduction, conventional therapy still consists of mastectomy with removal of the NAC, followed by reconstruction. Rising interest in improved cosmesis has led to the introduction of the skin-sparing and nipple-sparing mastectomy (NSM) as potential alternatives to mastectomy. There has been much controversy regarding the oncologic safety of these procedures, and the NSM has also introduced a set of complications, such as nipple and areolar necrosis, that are not a concern with total mastectomy. From our review of the literature, we feel that NSM may be a viable option in the appropriate setting, and that its risks and complications are acceptable when compared to the traditional surgical treatment of breast cancer.

Keywords: Nipple-sparing mastectomy, Risk reduction, Nipple–areolar complex preservation

Abbreviations: NAC, nipple–areolar complex, NSM, nipple-sparing mastectomy, BCT, breast-conservation therapy, DCIS, ductal carcinoma in situ