Surgical Oncology
Volume 15, Issue 1 , Pages 33-42, July 2006

Evaluation and management of incidentally discovered thyroid nodules

  • Rajiv V. Datta

      Affiliations

    • Division of Surgical Oncology and Head & Neck Surgery, South Nassau Cancer Center, 1 S. Central Avenue, Valley Stream, New York 11791, USA
    • Corresponding Author InformationCorresponding author. Tel.: +15166323350; fax: +15166323355.
    • ,
  • Nicholas J. Petrelli

      Affiliations

    • Helen F. Graham Cancer Center at Christiana Care Health System, 4701 Ogletown-Stanton Road, Newark, DE 19713, USA
    • ,
  • Joseph Ramzy

      Affiliations

    • Department of Otolaryngology, Helen F. Graham Cancer Center at Christiana Care Health System, 4701 Ogletown-Stanton Road, Newark, DE 19713, USA

Abstract 

Thyroid nodules are present in 4–10% of the adult population. However, less than 1% of all cancers occur in the thyroid gland. Thyroid nodules are usually an incidental finding in a routine clinical or an ultrasound examination of the neck performed for some other reason. Differentiating a benign nodule, which may require no specific treatment, from a malignant nodule presents a diagnostic dilemma. An individualized approach to a patient with history, risk factors and fine needle cytology is warranted. Molecular markers and immunohistochemical studies done on thyroid nodule cytology may help in differentiating benign from malignant. This article presents a review of the literature for the diagnosis and management of the thyroid nodule.

Keywords: Thyroid, Cancer, Nodule, Ultrasonography, Biopsy

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PII: S0960-7404(06)00026-0

doi:10.1016/j.suronc.2006.07.002

Surgical Oncology
Volume 15, Issue 1 , Pages 33-42, July 2006

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