Lessons from Coley's Toxin

Abstract

The active molecule in Coley's Toxin is not tumor necrosis factor (TNF) or endotoxin (LPS), but interleukin-12 (IL-12). IL-12 holds the key to improved anti-tumor immuns response.

Keywords: LPS, TNF, IL-12

Department of Surgery, Stanford University School of Medicine, Room H3591, 300 Pasteur Drive, Stanford, CA 94025, USA

Corresponding author.

PII: S0960-7404(06)00021-1

doi:10.1016/j.suronc.2006.05.002

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